Zebra GX420Rx

Zebra GX420RX


Designed specifically for secure prescription printing, Zebra’s GX420Rx works seamlessly with your hospital’s technology software, and complies with the Centers for Medicare & Medicaid Services (CMS) Tamper Resistant Prescription Law. Featuring multiple locking stations, Zebra’s GX420Rx printer contains an integrated lock to secure the prescription paper inside, along with a Kensington lock slot that enables you to attach the printer to a desk or table. The Rx printer is also available with a special mounting stand for additional security (stand sold separately).

With the direct print capability, Zebra’s GX420Rx increases patient safety by ensuring clear legibility, resulting in improved fill accuracy.

Please contact Zebra directly if you are interested in this printer.

*available in North America only

Zebra’s GX420Rx Healthcare Desktop Printer is used in the following industries: Healthcare.


Improve Patient Safety and Enhance Security

Available in a direct thermal model, the GK420Rx locking printer is designed specifically for secure prescription printing.

Increase Prescription Fill Accuracy

Ensure clear legibility by printing with the GX420Rx instead of handwriting prescriptions for increased fill accuracy. Produce prescriptions quickly with the printer’s 6-inches-per-second print speed.

Multiple Locks Provide Outstanding Security

Benefit from added tamper protection through the printer’s integrated lock that secures the paper inside, along with the Kensington® lock slot that enables you to attach the printer to a desk or table. For users looking for even more security, the printer is also available with a special mounting stand (stand sold separately).

Direct Thermal Printing Protects Patient Information

As a direct thermal printer, the GX420Rx helps you protect patient privacy. Since direct thermal printers don’t use a ribbon, there is no secondary record of the printed information that would require careful disposal.

Custom Supplies Reduce Possibility of Counterfeiting

Zebra offers custom media including color graphics and logos to reduce the risk of tampering or duplication.

Zebra OneCare Services

Increase printer uptime, and reduce lost productivity and unbudgeted repair costs, by selecting a Zebra® OneCare™ service agreement. A cost-effective means of planning and budgeting your annual maintenance expenditures, your agreement ensures that trained Zebra technicians will bring your printer back to factory specifications. Zebra offers a variety of plans to fit your budget and business needs.

Genuine Zebra Supplies

Ensure consistent print quality, reduce downtime and increase productivity in your printing process with Genuine Zebra™ supplies. We manufacture each supplies product with the exact same materials every time so you always get crisp, readable and scannable output without needing to adjust the printer darkness setting between rolls.


• Print method: Direct thermal
• Programming language: EPL™ and ZPL™
• Construction: Dual-wall frame
• Tool-less printhead and platen replacement
• OpenACCESS™ for easy media loading
• Auto-calibration of media
• Kensington lock slot
• Mechanical lock with 2 keys
• Feed key disabled
• Cutter for various roll-fed media
• ZebraNet 10/100 Print Server — Internal Ethernet for network communication
and printing
• ENERGY STAR qualified



4.09”/104 mm


203 dpi/8 dots per mm


6”/152 mm per second


Fixed reflective and transmissive sensors


GX models triple interface standard
RS-232 serial interface, DB-9
USB V1.1, bi-directional
ZebraNet 10/100 Print Server (internal)

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